Chondrogenic tumors

Topic Completed: 1 August 2013

Minor changes: 29 October 2019

Revised: 31 December 2018

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Chondroma[title]

Related topics: Enchondroma of hands and feet, Enchondromas of long bones, Calcifying enchondroma, Juxtacortical (periosteal) chondroma , Soft tissue (extraskeletal) chondromas

Nat Pernick, M.D.
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Cite this page: Pernick N Chondroma. website. Accessed May 26th, 2020.
Definition / general
  • Benign cartilaginous tumor
  • Either enchondroma (arise from diaphyseal medullary cavity), subperiosteal/juxtacortical chondroma or soft tissue chondroma
  • Cytofluorometric DNA ploidy analysis may be useful in distinguishing these tumors from chondrosarcomas (Mod Pathol 1999;12:863)
Molecular / cytogenetics description
  • 12q13-15 (HMGA2 / HMGI-C) is involved in structural rearrangements (also in other benign mesenchymal tumors, Mod Pathol 2003;16:1132)
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