Bone
Chondrogenic tumors
Enchondromas of long bones



Topic Completed: 1 August 2013

Revised: 31 October 2019

Copyright: 2003-2019, PathologyOutlines.com, Inc.

PubMed Search: Enchondromas [title] long bones

Nat Pernick, M.D.
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Page views in 2019 to date: 2,825
Cite this page: Pernick N. Enchondromas of long bones. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bonechondromaenchondromaslongbones.html. Accessed December 10th, 2019.
Definition / general
  • Enchondroma protuberans: rare, exaggeratedly eccentric enchondroma resembling osteochondroma radiologically (Hum Pathol 1982;13:734)
Radiology description
  • Well circumscribed tumor of metaphysis or diaphysis with flecks of calcification
  • Doesn’t invade the cortex
Radiology images

AFIP images

Enchondroma of distal femur

Enchondromatosis (Ollier disease)


 Contributed by Dr. Mark R. Wick

Tibia Xray

Multifocal in Ollier disease, CT scan

Distal femur Xray

Femur Xray

Gross description
  • Well circumscribed, pale blue, solid, no myxoid change
Gross images

Images hosted on Pathout server:

AFIP images

Enchondroma expands the rib


 Contributed by Dr. Mark R. Wick

Multifocal in Ollier disease

Microscopic (histologic) description
  • Hypocellular, few binucleated cells, may be multifocal but does not infiltrate marrow
  • No myxoid change
Microscopic (histologic) images

AFIP images

Quiz case

Islands of cartilage

Sparsely cellular cartilage

Cellular areas with moderate nuclear pleomorphism

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