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Bone chapter (nontumor and tumor)
Other tumors of bone
Erdheim-Chester disease

Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 7 February 2014, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.

See subtype below: hemophagocytosis associated variant

General
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Xray description
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Xray images
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CT scans, H&E, CD68, EM

Pathological fracture of left tibia

Case reports
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Micro description
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Micro images
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A/B-pleural and interlobular septal infiltrate with xanthomatous histiocytes and hemophagocytosis (arrows)
C/D: bone marrow has xanthomatous histiocytes and hematopoietic cells with hemophagocytosis (arrows)
E: CD68+ histiocytes
F: factor XIIIa+ histiocyte with hemophagocytosis (arrow)


Neck lymph node biopsy


Skin lesion biopsy

CD163+

Positive stains
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Negative stains
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Electron microscopy description
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Additional references
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Hemophagocytosis associated variant

Case report
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Micro description
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End of Bone chapter (nontumor and tumor) > Other tumors of bone > Erdheim-Chester disease


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