Home   Chapter Home   Jobs   Conferences   Fellowships   Books



Advertisement

Bone

Non-neoplastic or metabolic disease

Hyperostosis cranii ex vacuo


Reviewers: Dariusz Borys, M.D. (see Reviewers page)
Revised: 8 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.

General
=========================================================================

● Also called thickened calvarium
● May be due to intracranial hypotension associated with chronic shunting, as skull lacks the outward pressure needed to expand (Hum Pathol 1994;25:545)

Case reports
=========================================================================

● 23 year old woman with long standing ventriculoperitoneal shunt due to shaken baby syndrome (Arch Pathol Lab Med 2003;127:94)

Gross description
=========================================================================

● Circumferentially thickened skull, particularly inner table, involvement of calvarium and base

Gross images
=========================================================================



Thickened skull

Micro description
=========================================================================

● Increased cancellous space with normal trabecular bone

Micro images
=========================================================================



Figure 2B-increased cancellous space

Differential diagnosis of thickened calvarium
=========================================================================

● Pagetís disease, fibrous dysplasia, thalassemia, hyperostosis frontalis interna (inner table has varying thickness of lobulated bone)

End of Bone > Non-neoplastic or metabolic disease > Hyperostosis cranii ex vacuo


This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must be interpreted in the context of a patient's clinical data using reasonable medical judgment. This website should not be used as a substitute for the advice of a licensed physician.

All information on this website is protected by copyright of PathologyOutlines.com, Inc. Information from third parties may also be protected by copyright. Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).