Other tumors of bone
Implant related sarcoma

Topic Completed: 1 June 2005

Revised: 3 January 2019

Copyright: (c) 2003-2019,, Inc.

PubMed search: implant related sarcoma bone

Nat Pernick, M.D.
Page views in 2019: 60
Page views in 2020 to date: 29
Cite this page: Pernick N Implant related sarcoma. website. Accessed May 30th, 2020.
Definition / general
  • Uncommon but well recognized complication; sarcomas arise in bone or soft tissue at site of orthopedic hardware or a prosthetic joint
  • Mean 55 years old, usually male
  • Associated with hip arthroplasty for degenerative joint disease, intramedullary nail for fracture, staples for fixation or hardware for fracture fixation
  • Mean 11 years from hardware placement to sarcoma diagnosis
  • Usually osteosarcoma or malignant fibrous histiocytoma
  • Aggressive behavior with frequent metastases
Differential diagnosis
  • Infection
  • Reaction to prosthetic wear debris
Additional references
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