Implant related sarcoma

Bone
Other tumors of bone
Implant related sarcoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 19 October 2016, last major update June 2005

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: implant related sarcoma bone

Table of Contents

Definition / general | Radiology images | Gross images | Differential diagnosis | Additional references

Cite this page: Implant related sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneimplantrelated.html. Accessed July 14th, 2017.

Definition / general

Uncommon but well recognized complication; sarcomas arise in bone or soft tissue at site of orthopedic hardware or a prosthetic joint
Mean 55 years old, usually male
Associated with hip arthroplasty for degenerative joint disease, intramedullary nail for fracture, staples for fixation or hardware for fracture fixation
Mean 11 years from hardware placement to sarcoma diagnosis
Usually osteosarcoma or malignant fibrous histiocytoma
Aggressive behavior with frequent metastases

Radiology images

Images hosted on other servers:

Osteosarcoma surrounding implant

MFH surrounding intramedullary nail

Gross images

Images hosted on other servers:

Osteosarcoma adjacent to implant

Osteosarcoma with pathologic fracture

Differential diagnosis

Infection
Reaction to prosthetic wear debris

Additional references

Mod Pathol 2001;14:969