Bone
Other tumors of bone
Implant related sarcoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 20 July 2018, last major update June 2005

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed search: implant related sarcoma bone

Cite this page: Pernick, N. Implant related sarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneimplantrelated.html. Accessed September 25th, 2018.
Definition / general
  • Uncommon but well recognized complication; sarcomas arise in bone or soft tissue at site of orthopedic hardware or a prosthetic joint
  • Mean 55 years old, usually male
  • Associated with hip arthroplasty for degenerative joint disease, intramedullary nail for fracture, staples for fixation or hardware for fracture fixation
  • Mean 11 years from hardware placement to sarcoma diagnosis
  • Usually osteosarcoma or malignant fibrous histiocytoma
  • Aggressive behavior with frequent metastases
Differential diagnosis
  • Infection
  • Reaction to prosthetic wear debris
Additional references