General
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• Best evaluated on biopsy sections or imprints; particle sections are next best choice
• Aspirate smears may be difficult to evaluate, but are accurate (Am J Hematol 1986;22:381, Indian J Pathol Microbiol 1989;32:186)
• Theoretically could use automated hematology analyzer or flow cytometry (Ann Clin Lab Sci 2004;34:307)
• Iliac crest may not be representative if radiotherapy or other local insults
• Varies from 80% (children) to 55% (age 30) to <50% (age 60+)

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