Bone marrow - nonneoplastic
Systemic disorders
Podophyllin toxicity

Author: Nat Pernick, M.D. (see Authors page)

Revised: 28 June 2017, last major update December 2006

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Podophyllin toxicity

Cite this page: Podophyllin toxicity. website. Accessed October 24th, 2018.
Definition / general
  • Used as topical treatment of condyloma, although recommended to cease office based use due to toxicities (Sex Transm Infect 2001;77:409)
  • A mitotic spindle poison that binds microtubular proteins
  • Causes transient leukopenia and thrombocytopenia
  • Can also cause coma and death
Microscopic (histologic) description