Other tumors of bone
Massive osteolysis

Topic Completed: 1 June 2005

Revised: 3 January 2019

Copyright: (c) 2003-2019,, Inc.

PubMed search: massive osteolysis [title] bone

Nat Pernick, M.D.
Page views in 2019: 262
Page views in 2020 to date: 87
Cite this page: Pernick N Massive osteolysis. website. Accessed May 30th, 2020.
Definition / general
  • Also called Gorham disease
  • Resembles skeletal angiomatosis, but probably not a vascular neoplasm
  • Cause unknown
Gross description
  • Destructive reabsorption of a whole bone or several bones, with replacement by heavily vascularized fibrous tissue
Gross images

Markedly distorted proximal femur

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