Bone
Non-neoplastic or metabolic disease
Metal toxicity


Topic Completed: 1 August 2013

Revised: 27 December 2018

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PubMed Search: Bone[title]metal toxicity

Nat Pernick, M.D.
Page views in 2019: 60
Page views in 2020 to date: 23
Cite this page: Pernick N Metal toxicity. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bonemetaltoxicity.html. Accessed May 26th, 2020.
Definition / general
  • Causes: aluminum (from antacids), iron, fluoride
Microscopic (histologic) description
  • Increased osteoid, but well demarcated mineralization front and minimal osteoblasts
Positive stains
  • Aurintricarboxylic acid highlights aluminum
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