Bone
Osteomyelitis
General



Topic Completed: 1 June 2012

Revised: 27 December 2018

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Osteomyelitis bone[title]
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Cite this page: Borys D Osteomyelitis - general. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneosteomyelitisgeneral.html. Accessed May 23rd, 2019.
Definition / general
  • Infection of bone (osteitis) or bone marrow space (myelitis) = osteomyelitis
  • Usually pyogenic, fungal or tubercular
  • HIV+ patients may be infected by unusual organisms (eg. Mycobacterium avium)
  • Radiographically may resemble a neoplasm, particularly after antibiotic treatment
  • Severe osteomyelitis is not associated with grade IV sacral decubitus ulcers in non-septic patients; imaging may be misleading (Arch Pathol Lab Med 2003;127:1599)
  • May cause secondary AA amyloidosis
Radiology description
  • Permeative, destructive lesion with periosteal new bone formation
  • Chronic osteomyelitis may produce focal destruction or focal abscess
Radiology images

Contributed by Dr. Mark R. Wick
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Metatarsal xray

Microscopic (histologic) images

Contributed by Dr. Mark R. Wick
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Acute type



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Mild chronic osteomyelitis-figure 3

Additional references
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