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Osteomyelitis - general

Reviewers: Dariusz Borys, M.D. (see Reviewers page)
Revised: 9 August 2013, last major update June 2012
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.


● Infection of bone (osteitis) or bone marrow space (myelitis) = osteomyelitis
● Usually pyogenic, fungal or tubercular
● HIV+ patients may be infected by unusual organisms (eg. Mycobacterium avium)
● Radiographically may resemble a neoplasm, particularly after antibiotic treatment
● Severe osteomyelitis is not associated with grade IV sacral decubitus ulcers in non-septic patients - imaging may be misleading (Arch Pathol Lab Med 2003;127:1599)
● May cause secondary AA amyloidosis

Radiology description

● Permeative, destructive lesion with periosteal new bone formation
● Chronic osteomyelitis may produce focal destruction or focal abscess

Radiology images

Metatarsal xray - contributed by Dr. Mark R. Wick

Micro images

Acute type - contributed by Dr. Mark R. Wick

Mild chronic osteomyelitis-figure 3

Additional references

Massachusetts General Hospital

End of Bone > Osteomyelitis - general

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