Author: Dariusz Borys, M.D. (see Authors page)

Revised: 14 September 2016, last major update June 2012

Copyright: (c) 2003-2016,, Inc.

PubMed Search: Osteomyelitis bone[title]
Cite this page: Osteomyelitis - general. website. Accessed October 19th, 2018.
Definition / general
  • Infection of bone (osteitis) or bone marrow space (myelitis) = osteomyelitis
  • Usually pyogenic, fungal or tubercular
  • HIV+ patients may be infected by unusual organisms (eg. Mycobacterium avium)
  • Radiographically may resemble a neoplasm, particularly after antibiotic treatment
  • Severe osteomyelitis is not associated with grade IV sacral decubitus ulcers in non-septic patients; imaging may be misleading (Arch Pathol Lab Med 2003;127:1599)
  • May cause secondary AA amyloidosis
Radiology description
  • Permeative, destructive lesion with periosteal new bone formation
  • Chronic osteomyelitis may produce focal destruction or focal abscess
Radiology images

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Metatarsal xray - contributed by Dr. Mark R. Wick

Microscopic (histologic) images

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Acute type - contributed by Dr. Mark R. Wick

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Mild chronic osteomyelitis-figure 3

Additional references