Bone
Nonneoplastic or metabolic disease
Osteopoikilosis


Topic Completed: 1 August 2013

Revised: 27 December 2018

Copyright: (c) 2003-2018, PathologyOutlines.com, Inc.

PubMed Search: Osteopoikilosis[title]

Nat Pernick, M.D.
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Cite this page: Pernick N Osteopoikilosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/boneosteopoikilosis.html. Accessed May 30th, 2020.
Definition / general
  • Usually autosomal dominant with high penetrance
  • No symptoms, no abnormal labs
  • Associated with osteosarcoma in affected bone, scleroderma, other conditions
Radiology description
  • Multiple sclerotic, round lesions of variable size in cancellous bone near joint surfaces
Microscopic (histologic) description
  • Resembles bone island
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