Nonneoplastic or metabolic disease

Topic Completed: 01 August 2013

Revised: 27 December 2018

Copyright: (c) 2003-2018,, Inc.

PubMed Search: Osteopoikilosis[title]
Page views in 2018: 141
Page views in 2019 to date: 4
Cite this page: Pernick N Osteopoikilosis. website. Accessed January 21st, 2019.
Definition / general
  • Usually autosomal dominant with high penetrance
  • No symptoms, no abnormal labs
  • Associated with osteosarcoma in affected bone, scleroderma, other conditions
Radiology description
  • Multiple sclerotic, round lesions of variable size in cancellous bone near joint surfaces
Microscopic (histologic) description
  • Resembles bone island