Bone chapter (nontumor and tumor)
Non-neoplastic or metabolic disease
Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 29 July 2013, last major update June 2005
Copyright: (c) 2003-2013, PathologyOutlines.com, Inc.
- Synovitis, Acne, Pustulosis, Hyperostosis and Osteitis
- Variable and nonspecific histologic findings
- Often peculiar bone lesions of anterior chest wall and pustular dermatoses
- Mean age 35 years, range 5-63 years
- Early lesions resemble bacterial osteomyelitis with acute inflammation, edema, prominent periosteal bone formation
- Late lesions have markedly sclerotic bony trabeculae with prominent marrow fibrosis and mild chronic inflammation
End of Bone chapter (nontumor and tumor) > Non-neoplastic or metabolic disease > SAPHO syndrome
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