Table of ContentsDefinition / General | Radiology Images | Micro Description | Micro Images | Positive Stains
Cite this page: Sinus histiocytosis with massive lymphadenopathy. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bonesinushistio.html. Accessed December 5th, 2016.
Definition / General
- Also called Rosai-Dorfman disease
- Rare; unknown cause
- Skeleton is fifth most common site of extranodal involvement
- Fibrosis, polyclonal plasma cells, lymphocytes, histiocytes, lymphocytophagocytosis by histiocytes
- S100 (histiocytes)