Table of ContentsDefinition / General | Micro Description | Micro Images | Positive Stains | Negative Stains | Electron Microscopy Description | Differential Diagnosis | Additional References
Cite this page: Small cell osteosarcoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bonesmallcellosteo.html. Accessed December 3rd, 2016.
Definition / General
- Very rare
- Poor prognosis
- Diffuse growth of small, uniform, round/spindle tumor cells, focally produces malignant osteoid, occasionally mixed with cartilage
Electron Microscopy Description
- High N/C ratio, poorly differentiated cytoplasm, numerous free ribosomes and mitochondria, small junctions, envelopment of individual and groups of cells by matrix (Hum Pathol 1991;22:267)