Bone
Other tumors of bone
Subungual keratoacanthoma

Author: Nat Pernick, M.D. (see Authors page)

Revised: 17 October 2016, last major update June 2005

Copyright: (c) 2003-2016, PathologyOutlines.com, Inc.

PubMed search: Subungual keratoacanthoma

Cite this page: Subungual keratoacanthoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/bonesubungualKA.html. Accessed December 4th, 2016.
Definition / General
  • Rare; well circumscribed nail bed lesion producing lytic defects in underlying bone
  • Rapidly progressive
  • Benign; excision is curative
Radiology Description
  • Well defined defect in bone
Micro Description
  • Proliferation of squamous cells with abundant pink cytoplasm and marked keratinization, resembling cutaneous lesion
Differential Diagnosis
  • Squamous cell carcinoma: usually a chronic problem, tends to permeate bone