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Xanthogranulomatous osteomyelitis

Reviewers: Dariusz Borys, M.D. (see Reviewers page)
Revised: 8 June 2012, last major update June 2012
Copyright: (c) 2003-2012, PathologyOutlines.com, Inc.


● Osteomyelitic lesions
● Histologically characterized by prominent foam macrophages arranged in a mosaic pattern with neutrophil infiltration, foam cell formation, numerous plasma cells, fibrin precipitates
● Involving rib, tibial epiphysis, ulna, distal tibia and femur
● Young individuals are more commonly affected

Case reports

● Two cases with prominent foamy macrophages, neutrophils, plasma cells and fibrin (Arch Pathol Lab Med 1984;108:973)
● Xanthogranulomatous osteomyelitis (J Orthop Traumatol 2011 Nov 11 [Epub ahead of print])

End of Bone > Osteomyelitis > Xanthogranulomatous osteomyelitis

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