Bone & joints
Other tumors

Topic Completed: 1 June 2005

Revised: 4 January 2019

Copyright: (c) 2003-2019,, Inc.

PubMed search: xanthoma [title] bone

Nat Pernick, M.D.
Page views in 2019: 570
Page views in 2020 to date: 332
Cite this page: Pernick N Xanthoma. website. Accessed August 14th, 2020.
Definition / general
  • 65% male, age 20+ years
  • Usually solitary; affects pelvis, ribs, skull
Radiology description
  • Well defined, expansile lytic lesion, often with sclerotic margin
Microscopic (histologic) description
  • Foam cells, multinucleated giant cells, cholesterol clefts, fibrosis
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