Breast nonmalignant
Chronic inflammation

Topic Completed: 1 March 2010

Minor changes: 3 September 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Chronic inflammation [title] breast

Hind Warzecha, M.D.
Page views in 2019: 2,037
Page views in 2020 to date: 791
Cite this page: Nassar H. Chronic inflammation. website. Accessed May 27th, 2020.
Definition / general
  • Nonspecific finding of chronic inflammatory cells, not part of other inflammatory entities
  • Common
  • Associated with cyst rupture and release of secretions into stroma
Differential diagnosis
  • Duct ectasia: also dilated large ducts with fibrous thickening of wall, elastic fibers in wall and foamy macrophages in lumen
  • Foreign body reaction: also foreign body giant cells, fat necrosis, calcification, cholesterol clefts
  • Lymphocytic mastitis: ill defined lesion of dense intralobular, perilobular and perivascular lymphocytes with lobular atrophy and sclerosis, B cell lymphoepithelial lesions, lymphoid follicles with germinal centers
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