Breast - nonmalignant
Inflammatory / infectious
Chronic inflammation

Author: Hind Nassar, M.D. (see Authors page)

Revised: 25 July 2017, last major update March 2010

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Chronic inflammation [title] breast

Cite this page: Chronic inflammation. website. Accessed December 12th, 2018.
Definition / general
  • Nonspecific finding of chronic inflammatory cells, not part of other inflammatory entities
  • Common
  • Associated with cyst rupture and release of secretions into stroma
Differential diagnosis
  • Duct ectasia: also dilated large ducts with fibrous thickening of wall, elastic fibers in wall and foamy macrophages in lumen
  • Foreign body reaction: also foreign body giant cells, fat necrosis, calcification, cholesterol clefts
  • Lymphocytic mastitis: ill defined lesion of dense intralobular, perilobular and perivascular lymphocytes with lobular atrophy and sclerosis, B cell lymphoepithelial lesions, lymphoid follicles with germinal centers