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General
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Terminology
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Epidemiology
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Etiology
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Clinical features
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Treatment
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Micro description
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Micro images
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Florid simple, courtesy of Dr. Mark R. Wick

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Distention of duct by cellular proliferation with irregular and slit-like spaces

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Oval/spindled epithelial cells and elongated with dense chromatin

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Micropap. ductal hyperplasia w/ parallel arrangement of most cells and uniform nuclei

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Secondary lumina have irregular shapes

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Apocrine metaplasia forming secondary lumina with foam cells

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Perineural invasion

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Mild hyperplasia

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Florid hyperplasia

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Proliferating cells form solid sheets

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Cribriform pattern

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Without nuclear atypia

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Compact florid hyperplasia

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Spaces irregular and appear compressible

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Fibrocystic changes

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Usual ductal hyperplasia (CK903+) versus ADH (CK903-)

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Secondary lumina adjacent to basement membrane
are more rounded than smaller central lumina
and cell population is heterogeneous

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Spindled epithelial cells parallel
to long axis of intraductal
cellular bridges;
cell bridges merge to form
secondary lumina;
myoepithelial cell present
along borders

Videos
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Cytology description
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Cytology images
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With apocrine metaplasia

Positive stains
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End of Breast - nonmalignant > Fibrocystic disease > Epithelial ductal hyperplasia of breast



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