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Fibrocystic disease

Fibroadenomatoid change


Reviewer: Hind Nassar, MD, Johns Hopkins Medical Institute

Revised: 7 October 2012, last major update June 2010

Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.




● An incidental finding, usually in a background of fibrocystic change




● Also called fibroadenomatoid hyperplasia, fibroadenomatoid mastopathy


Clinical features


● Incidence of 11% (Pathology 1987;19:393, Malays J Pathol 1991;13:101)

Radiology: suspicious, granular, clustered microcalcifications on screening mammography (AJR Am J Roentgenol 1998;171:1331)


Micro description (Histopathology)


● Proliferation of intralobular connective tissue that resembles microscopic foci of fibroadenoma without an actual mass and without the typical circumscription of a fibroadenoma

● Often coexists with dilated ducts, epithelial hyperplasia, adenosis, calcifications


Micro images



Fibroadenomatoid focus


End of Breast-nonmalignant > Fibrocystic disease > Fibroadenomatoid change



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