Home   Chapter Home   Jobs   Conferences   Fellowships   Books

 

 

Advertisement 

 

Breast-nonmalignant

Parasites

Filariasis

 

Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)

Revised: 1 October 2012, last major update March 2010

Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

 

Definition

=========================================================================

● Infestation due to nematode parasites of the order Filariidae

 

Terminology

=========================================================================

 

Epidemiology

=========================================================================

 

Sites

=========================================================================

 

Etiology

=========================================================================

● Usually due to Filaria bancroftii, formerly called Wucheria bancroftii

 

Clinical features

=========================================================================

Usually involves lymphatics or lymph nodes, rare in breast

May occur years after leaving endemic area

 

Prognostic factors

=========================================================================

 

Case reports

=========================================================================

● Breast mass 3 years after visit to India (Archives 1987;111:757)

● 59 year old woman with granuloma in breast (Indian J Pathol Microbiol 2008;51:85)

● 69 year old Nigerian woman visiting US (Radiology 2002;222:515)

● Dirofilariasis in Hong Kong diagnosed by FNA (Diagn Cytopathol 2002;26:22)

 

Treatment

=========================================================================

 

Clinical images

=========================================================================

 

Gross description (Macroscopy)

=========================================================================

 

Gross images

=========================================================================

 

Micro description (Histopathology)

=========================================================================

● Adult worms, preserved or degenerating

● Granulomatous inflammation with eosinophilic abscesses

 

Micro images

=========================================================================

 

                                                                      

AFIP Fig 30: gravid female worm of Wucheria            Transverse section of adult filarial

bancrofti in exudate surrounded by fibrosis               worm with granuloma

 

Drawings

=========================================================================

 

Virtual Slides

=========================================================================

 

Videos

=========================================================================

 

Cytology description

=========================================================================

● Eosinophils, ova, embryonated eggs (Indian J Pathol Microbiol 2006;49:365)

Also fragments of adult worms, gravid female worms, microfilariae, macrophages, variable epithelioid granulomas, other acute or chronic inflammatory cells (Diagn Cytopathol 2010 Jan 20 [Epub ahead of print])

● Filariasis may be detected in a clinically unsuspected case, especially in an endemic zone (Diagn Cytopathol 2009 Nov 25 [Epub ahead of print])


Negative stains

=========================================================================

 

Electron microscopy descriptions

=========================================================================

 

Electron microscopy images

=========================================================================

 

Molecular / cytogenetics description

=========================================================================

 

Molecular / cytogenetics images

=========================================================================

 

 

Differential Diagnosis

=========================================================================

 

Additional references

=========================================================================

eMedicine #1, #2

 

End of Breast-nonmalignant > Parasites > Filariasis

 

 

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must also be interpreted in the context of a patient's clinical data using reasonable medical judgment.  This website should not be used as a substitute for the advice of a licensed physician.

 

All information on this website is protected by copyright of PathologyOutlines.com, Inc.  Information from third parties may also be protected by copyright.  Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).