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Breast-nonmalignant
Parasites
Filariasis
Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)
Revised: 1 October 2012, last major update March 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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● Infestation due to nematode parasites of the order Filariidae
Terminology
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Epidemiology
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Sites
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Etiology
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● Usually due to Filaria bancroftii, formerly called Wucheria bancroftii
Clinical features
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● Usually involves lymphatics or lymph nodes, rare in breast
● May occur years after leaving endemic area
Prognostic factors
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Case reports
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● Breast mass 3 years after visit to India (Archives 1987;111:757)
● 59 year old woman with granuloma in breast (Indian J Pathol Microbiol 2008;51:85)
● 69 year old Nigerian woman visiting US (Radiology 2002;222:515)
● Dirofilariasis in Hong Kong diagnosed by FNA (Diagn Cytopathol 2002;26:22)
Treatment
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Clinical images
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Gross description (Macroscopy)
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Gross images
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Micro description (Histopathology)
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● Adult worms, preserved or degenerating
● Granulomatous inflammation with eosinophilic abscesses
Micro images
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AFIP Fig 30: gravid female worm of Wucheria Transverse section of adult filarial
bancrofti in exudate surrounded by fibrosis worm with granuloma
Drawings
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Virtual Slides
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Videos
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Cytology description
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● Eosinophils, ova, embryonated eggs (Indian J Pathol Microbiol 2006;49:365)
● Also fragments of adult worms, gravid female worms, microfilariae, macrophages, variable epithelioid granulomas, other acute or chronic inflammatory cells (Diagn Cytopathol 2010 Jan 20 [Epub ahead of print])
● Filariasis may be detected in a clinically unsuspected case, especially in an endemic zone (Diagn Cytopathol 2009 Nov 25 [Epub ahead of print])
Negative stains
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Electron microscopy descriptions
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Electron microscopy images
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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Differential Diagnosis
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Additional references
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● eMedicine #1, #2
End of Breast-nonmalignant > Parasites > Filariasis
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