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Breast-nonmalignant
Inflammatory / infectious
Fungal infections
Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)
Revised: 27 September 2012, last major update April 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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Terminology
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● Fungal mastitis
Epidemiology
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● Uncommon
Sites
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Etiology
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Clinical features
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● Actinomycosis may develop in nipple and cause formation of a sinus tract
● Report of saline filled breast implants contaminated with Curvularia in 5 patients (J Infect Dis 2005;192:170)
● Candida infection may interfere with breast feeding, but Candida albicans is not present in milk ducts in women with clinical symptoms of ductal candidiasis (Breastfeed Med 2009;4:57)
Prognostic factors
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Case reports
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● Immunosuppressed patient with breast nodule due to coccidiomycosis (Arch Pathol Lab Med 1991;115:1064)
● Cryptococcus in HIV+ patient (J Infect 2008;57:82)
● Fusarium in 55 year old woman with diabetes (Indian J Med Microbiol 2005;23:198)
● Histoplasma capsulatum causing granulomatous mastitis (Hum Pathol 1989;20:47, Arch Pathol Lab Med 2006;130:e1)
● Trichophyton rubrum causing bilateral male breast enlargement (Breast 2006;15:263)
Treatment
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Clinical images
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Gross description (Macroscopy)
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Gross images
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Micro description (Histopathology)
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Micro images
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Fusarium - Clinical image and FNA smears
Histoplasma capsulatum
Fig 1: necrotizing granulomatous inflammation
Fig 2/3: histiocytes contain multiple intracellular organisms with peripheral clearing
Fig 4: GMS shows yeast with narrow-based buds and nonbudding yeast
Drawings
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Virtual Slides
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Videos
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Cytology description
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Cytology images
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Positive stains
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Negative stains
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Electron microscopy descriptions
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Electron microscopy images
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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Differential Diagnosis
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● (link to topic)
Additional references
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End of Breast-nonmalignant > Inflammatory / infectious > Fungal infections
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