Benign tumors / changes
Juvenile xanthogranuloma

Author: Monika Roychowdhury, M.D., FCAP (see Authors page)

Revised: 8 August 2017, last major update April 2010

Copyright: (c) 2002-2017,, Inc.

PubMed Search: Breast juvenile xanthogranuloma
Cite this page: Juvenile xanthogranuloma. website. Accessed March 22nd, 2018.
Definition / general
  • Benign histiocytic disorder of skin, very rare in breast tissue itself
  • See also topic under Soft tissue tumors
  • Also called nevoxanthoendothelioma
  • Benign histiocytic disorder of infants and children; 15% occur in adults (usually young)
Radiology images

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Figure 2: Breast
A: Mammogram
B: Sonogram
C: Doppler sonography

Case reports
  • Conservative excision
Gross description
  • Cutaneous lesions usually 0.1 to 2.0 cm, yellow red and papulonodular
Microscopic (histologic) description
Microscopic (histologic) images

Images hosted on PathOut server:

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Figure 3: Diffuse nodular
aggregation of histiocytes
intermingled with chronic
inflammatory cells

Positive stains
Negative stains
Differential diagnosis