Breast nonmalignant
Benign tumors

Topic Completed: 1 April 2010

Minor changes: 10 September 2019

Copyright: 2002-2019,, Inc.

PubMed Search: Leiomyoma [title] breast

Hind Warzecha, M.D.
Page views in 2019: 1,036
Page views in 2020 to date: 536
Cite this page: Warzecha H. Leiomyoma. website. Accessed May 31st, 2020.
Definition / general
  • Benign smooth muscle tumor similar to counterparts elsewhere
  • Rare in breast
  • Usually involves nipple
Clinical features
Case reports
  • Complete excision to prevent recurrence
Clinical images

Contributed by Dr. Mark R. Wick

Breast skin

Gross description
  • Often ill defined
Microscopic (histologic) description
  • Interlacing bundles of spindle cells with eosinophilic cytoplasm and blunt ended, cigar shaped nuclei
  • May have epithelioid or granular features
  • No atypia, no hypercellularity, no / rare mitotic figures ( < 3 per 10 HPF), no necrosis
Microscopic (histologic) images

AFIP images

Circumscribed tumor of spindled cells without atypia

 Contributed by Dr. Mark R. Wick

Breast skin

Images hosted on other servers:

Spindled cells with rounded ends

Negative stains
Differential diagnosis
Back to top