Home   Chapter Home   Jobs   Conferences   Fellowships   Books

 

 

Advertisement 

 

Breast-nonmalignant

Benign tumors / changes

Lipoma of breast

 

Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)

Revised: 8 October 2012, last major update April 2010

Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

 

Definition

=========================================================================

● Tumor of mature fat cells without atypia

 

Terminology

=========================================================================

● See also angiolipoma, chondrolipoma, spindle cell lipoma

 

Epidemiology

=========================================================================

● Most common benign tumor of male and female breast

● Usually ages 40-60 years

 

Sites

=========================================================================

● Usually subcutaneous; less often intramammary

 

Etiology

=========================================================================

 

Clinical features

=========================================================================

● Asymptomatic, mobile, solitary

● Recommended to confirm clinical and radiologic impression of lipoma with FNA, core biopsy or excision if necessary (Breast 2004;13:408)

 

Prognostic factors

=========================================================================

 

Case reports

=========================================================================

● 58 year old woman with giant lipoma of underlying pectoralis muscle simulating malignancy (Ann Acad Med Singapore 2005;34:275)

 

Treatment

=========================================================================

● Excision usually not necessary, except to exclude other diagnoses

 

Clinical images

=========================================================================

 

Gross description (Macroscopy)

=========================================================================

● Well circumscribed, thinly encapsulated, usually < 5 cm

 

Gross images

=========================================================================

 

Micro description (Histopathology)

=========================================================================

● Sheets of mature adipocytes without lipoblasts or atypia

● Resembles surrounding fat

 

Micro images

=========================================================================

 

  

Mature adipose tissue without atypia

 

Virtual Slides

=========================================================================

 

Videos

=========================================================================

 

Cytology description

=========================================================================

● Fat cells

 

Cytology images

=========================================================================

 

Positive stains

=========================================================================

● S100, CD34

 

Negative stains

=========================================================================

 

Electron microscopy descriptions

=========================================================================

 

Electron microscopy images

=========================================================================

 

Molecular / cytogenetics description

=========================================================================

 

Molecular / cytogenetics images

=========================================================================

 

 

Differential Diagnosis

=========================================================================

● Fatty area of breast tissue without encapsulation

 

Additional references

=========================================================================

 

End of Breast-nonmalignant > Benign tumors / changes > Lipoma

 

 

This information is intended for physicians and related personnel, who understand that medical information is often imperfect, and must also be interpreted in the context of a patient's clinical data using reasonable medical judgment.  This website should not be used as a substitute for the advice of a licensed physician.

 

All information on this website is protected by copyright of PathologyOutlines.com, Inc.  Information from third parties may also be protected by copyright.  Please contact us at copyrightPathOut@gmail.com with any questions (click here for other contact information).