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Breast-nonmalignant

Inflammatory / infectious

Lupus mastitis

 

Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)

Revised: 27 September 2012, last major update April 2010

Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.

 

Definition

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● A subset of breast-limited lupus panniculitis

 

Terminology

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Epidemiology

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Sites

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Etiology

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Clinical features

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Prognostic factors

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Case reports

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● 33 year old woman with SLE and acute breast pain (J Obstet Gynaecol Res 2008;34:919)

● 44 year old woman with lupus nephritis but no systemic disease (AJR Am J Roentgenol 2002;178:1233)

 

Treatment

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● Usually medical

● Surgery may exacerbate condition (Adv Anat Pathol 2009;16:56)

 

Clinical images

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Gross description (Macroscopy)

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● Usually involves deep subcutis

 

Gross images

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Micro description (Histopathology)

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● Necrotizing vasculitis, fat necrosis with microcalcifications, hyaline sclerosis of adipose

● Also lymphocytic infiltration surrounding the necrosis, panniculitis and changes of discoid lupus erythematosis in overlying skin (Indian J Radiol Imaging 2009;19:170)

 

Micro images

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Perivascular lymphocytic infiltrate                Dense fibrosis with calcifications

 

Virtual Slides

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Videos

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Cytology description

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Cytology images

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Positive stains

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Negative stains

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Electron microscopy descriptions

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Electron microscopy images

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Molecular / cytogenetics description

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Molecular / cytogenetics images

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Differential Diagnosis

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Additional references

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End of Breast-nonmalignant > Inflammatory / infectious > Lupus mastitis

 

 

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