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Breast-nonmalignant
Inflammatory / infectious
Lupus mastitis
Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)
Revised: 27 September 2012, last major update April 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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● A subset of breast-limited lupus panniculitis
Terminology
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Epidemiology
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Sites
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Etiology
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Clinical features
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Prognostic factors
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Case reports
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● 33 year old woman with SLE and acute breast pain (J Obstet Gynaecol Res 2008;34:919)
● 44 year old woman with lupus nephritis but no systemic disease (AJR Am J Roentgenol 2002;178:1233)
Treatment
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● Usually medical
● Surgery may exacerbate condition (Adv Anat Pathol 2009;16:56)
Clinical images
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Gross description (Macroscopy)
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● Usually involves deep subcutis
Gross images
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Micro description (Histopathology)
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● Necrotizing vasculitis, fat necrosis with microcalcifications, hyaline sclerosis of adipose
● Also lymphocytic infiltration surrounding the necrosis, panniculitis and changes of discoid lupus erythematosis in overlying skin (Indian J Radiol Imaging 2009;19:170)
Micro images
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Perivascular lymphocytic infiltrate Dense fibrosis with calcifications
Virtual Slides
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Videos
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Cytology description
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Cytology images
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Positive stains
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Negative stains
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Electron microscopy descriptions
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Electron microscopy images
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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Differential Diagnosis
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Additional references
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End of Breast-nonmalignant > Inflammatory / infectious > Lupus mastitis
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