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General
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Micro description / grading
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Micro images
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H&E

3-fold variation in nuclear size - H&E

Abundant granular eosinophilic cytoplasm

Low, intermediate and high power


Cells have abundant cytoplasm, vesicular nuclei and prominent nucleoli (AFIP)

51 year old woman with apocrine DCIS in adenosis with Paget's disease of the breast, Contributed by: Dr. Semir Vranic (Bosnia)


Micropapillary pattern

Cribriform pattern

Androgen receptor staining

p53

Granular cytoplasm

Involving lobules


Forming tufts

Secretory features

Positive stains
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High grade apocrine DCIS

Positive stains
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Negative stains
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Differential diagnosis
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Additional references
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End of Breast malignant, males, children > In situ carcinoma > Apocrine DCIS



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