Breast malignant, males, children
In situ carcinoma
Clinging DCIS

Author: Dina Kandil, M.D. (see Authors page)

Revised: 18 October 2016, last major update January 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Clinging DCIS

Cite this page: Clinging DCIS. website. Accessed October 24th, 2018.
Definition / general
  • Terminology is no longer widely used
  • Typically used to describe high-grade DCIS with comedonecrosis, in which the necrosis is so extensive that only 1 or 2 layers are present at the periphery
  • Although controversial, it is preferable not to use this term to describe columnar cell hyperplasia with atypia or flat epithelial lesion, to avoid overtreatment (Breast Cancer Res 2003;5:263)
Microscopic (histologic) description
  • 1 - 2 layers of malignant cells lining a gland with a large empty lumen
  • Tumor cells are highly atypical and often associated with extensive comedo necrosis
Differential diagnosis
  • Flat epithelial atypia: dilated ducts lined by 1 or several layers of cuboidal or columnar cells with atypia resembling low grade DCIS; prominent apical cytoplasmic snouts are very common