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General
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Terminology
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Epidemiology
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Prognostic features
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Case reports
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Clinical images
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17 year old boy with breast mass and skin involvement

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7 year old Ethiopian girl with breast mass present for 2 years

Gross description
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Micro description
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Micro images
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H&E, PAS

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Intracytoplasmic lumen, H&E

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Courtesy of Dr. Mark R. Wick

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Case of Week #8

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Arising within radial scar

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Intracytoplasmic lumina with secretions

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Well-differentiated but invasive glands

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PAS, S100, E-cadherin

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S-100+

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PAS+ diastase resistant secretions

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S100, EMA, pan cytokeratin, ER

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Various images



AFIP images:
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Intraductal component with microcystic features

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Microcystic pattern below, solid apocrine pattern above

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Secretion tends to shrink toward center of lumen, may have a scalloped border in larger microcysts

Cytology description
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Positive stains
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Negative stains
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Molecular description
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Molecular images
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FISH shows t(12;15)

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t(12;15) in 6 year old girl

Electron microscopy description
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Electron microscopy images
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Large irregular cytoplasmic vacuoles lined by villi (AFIP)

Differential diagnosis
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Additional references
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End of Breast malignant, males, children > Carcinoma subtypes > Secretory carcinoma



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