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See variants: alveolar, basal-like, histiocytoid, pleomorphic, signet-ring, solid, trabecular

General
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Clinical features
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Case reports
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Treatment
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Clinical images
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Mammogram, courtesy of Dr. Mark R. Wick

Gross description
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Gross images
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Solid firm mass

Infiltration into adipose tissue

Anal metastasis

Multiple foci with irregular margins

Micro description
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Micro images
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Single dyscohesive cells

Classic features

Targetoid pattern


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Foci of tumor cells may be inconspicuous

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Mimicking fat necrosis

Minute focus (arrow) of tumor around a small duct (AFIP)

Prominent intracytoplasmic mucin

Tumor of male breast


With LCIS


Grade I of III-minimal nuclear pleomorphism

Grade II of III-moderate nuclear pleomorphism

Grade III of III-severe nuclear pleomorphism



Images courtesy of Dr. Mark R. Wick:

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Sheet like

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Alcian blue stain

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Estrogen receptor

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Type 3



Invasive lobular carcinoma within fibroadenoma:

Left to right: H&E (2), ER, CK5/6, E-cadherin



Metastases:

Endometrial polyp: H&E and AE1/AE3

Lymph node

Soft tissue

Stomach

Cytology description
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Cytology images
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Small cells arranged in linear pattern (figure B)

Various images

Positive stains
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Negative stains
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Molecular description
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Electron microscopic images
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Line of tumor cells surrounded by collagen, with cytokeratin bundles (arrows), but no basement membrane

Intracytoplasmic lumina lined by microvilli, elastic tissue (arrows) and collagen in stroma

Intracytoplasmic lumen with numerous microvilli and perinuclear mucin granules

Videos
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Differential diagnosis
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End of Breast malignant, males, children > Carcinoma subtypes > Classic infiltrating lobular carcinoma


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