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General
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Clinical features
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Case reports
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Micro description
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Micro images
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Courtesy of Dr. Mark R. Wick

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Mixed classic and signet ring morphology

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Contributed by: Dr. Semir Vranic, University of Sarajevo (Bosnia)

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Prominent signet ring cells

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Vacuolated cytoplasm with crescentic nuclei

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AFIP

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Associated with papilloma

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Vacuolated cytoplasm with crescentic nuclei

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E-cadherin, by Dr. Semir Vranic

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CK8

Positive stains
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Negative stains
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Electron microscopy
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Differential diagnosis
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Additional references
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End of Breast malignant, males, children > Carcinoma subtypes > Signet ring variant of lobular carcinoma



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