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Breast malignant, males, children
Carcinoma subtypes
Lobular carcinoma - solid variant

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 28 October 2016, last major update August 2012

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PubMed Search: Solid variant of lobular carcinoma

Table of Contents
Definition / general | Clinical features | Case reports | Microscopic (histologic) images | Differential diagnosis
Cite this page: Lobular carcinoma - solid variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantlobularsolid.html. Accessed July 14th, 2017.
Definition / general
  • First described in 1975 (Hum Pathol 1975;6:373)
  • Cells grow in sheets that engulf normal structures and infiltrate fat, but have cytologic features of classic lobular carcinoma
  • Little intervening stroma present
  • Resembles lymphoma
Clinical features
  • In 1989, represented 6% of all lobular carcinomas, and had poorest survival of all subtypes (Br J Cancer 1989;60:605)
Case reports
Microscopic (histologic) images

Images hosted on other servers:

Diffuse tumor cell infiltration

Solid pattern, but cells are still separate and distinct

Pan-keratin

E-cadherin

Differential diagnosis
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