Breast malignant, males, children
Carcinoma subtypes
Lobular carcinoma - solid variant


Topic Completed: 1 August 2012

Revised: 12 April 2019

Revised: 23 January 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Solid variant of lobular carcinoma


Monika Roychowdhury, M.D.
Page views in 2018: 1,216
Page views in 2019 to date: 764
Cite this page: Roychowdhury M Lobular carcinoma - solid variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantlobularsolid.html. Accessed July 19th, 2019.
Definition / general
  • First described in 1975 (Hum Pathol 1975;6:373)
  • Cells grow in sheets that engulf normal structures and infiltrate fat, but have cytologic features of classic lobular carcinoma
  • Little intervening stroma present
  • Resembles lymphoma
Clinical features
  • In 1989, represented 6% of all lobular carcinomas, and had poorest survival of all subtypes (Br J Cancer 1989;60:605)
Case reports
Microscopic (histologic) images

Images hosted on other servers:

Diffuse tumor cell infiltration

Solid pattern, but cells are still separate and distinct

Pan-keratin

E-cadherin

Differential diagnosis
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