Breast malignant, males, children
Carcinoma subtypes
Lobular carcinoma - trabecular variant

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 28 October 2016, last major update August 2012

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PubMed Search: Trabecular variant of lobular carcinoma

Cite this page: Lobular carcinoma - trabecular variant. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantlobulartrabecular.html. Accessed December 4th, 2016.
Definition / General
  • Classic lobular carcinoma infiltrating in trabeculae (linear bands) two to four cells thick
  • Trabecula - supporting beam of bar, plural is trabeculae
  • Trabeculae variant is usually not considered a distinct variant because it overlaps the classic and mixed patterns (Schnitt: Biopsy Interpretation of the Breast, 2nd Edition, 2009)
Electron Microscopy Description
  • Tumor cells are similar to classic lobular carcinoma (J Pathol 1985;145:39)
  • Compared to LCIS, tumor cells are more irregular, with more organelles and filaments