Breast malignant, males, children - Trabecular variant of lobular carcinoma

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Breast malignant, males, children

Carcinoma subtypes

Trabecular variant of lobular carcinoma

Reviewer: Monika Roychowdhury, M.D., (see Reviewers page)
Revised: 15 November 2012, last major update August 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

General
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● Classic lobular carcinoma infiltrating in trabeculae (linear bands) two to four cells thick
● Trabecula - supporting beam of bar, plural is trabeculae
● Trabeculae variant is usually not considered a distinct variant because it overlaps the classic and mixed patterns (Schnitt, Stuart J. (2009). Biopsy interpretation of the breast. Philadelphia, PA: Lippincott Williams & Wilkins.)

Electron microscopy description
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● Tumor cells are similar to classic lobular carcinoma (J Pathol 1985;145:39)
● Compared to LCIS, tumor cells are more irregular, with more organelles and filaments

End of Breast malignant, males, children > Carcinoma subtypes > Trabecular variant of lobular carcinoma

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