Table of ContentsClinical Features | Radiology Description | Case Reports | Micro Description | Micro Images
Cite this page: Metastases to male breast. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantmalemets.html. Accessed March 30th, 2017.
- 2% of all nonhematologic breast malignancies
- Most common primary is melanoma; also prostate (Urology 1978;11:641), colon, lung and bladder (Virchows Arch 2006;449:507)
- Prostate metastases are often bilateral, usually after estrogen therapy in background of gynecomastia; PSA+, PAP+ (note that the normal male breast and gynecomastia may be PSA+ but PAP-, Breast Cancer Res 2004;6:R18, Hum Pathol 1991;22:242)
- Need strong index of suspicious to diagnose, may need immunostains to distinguish primary and metastatic disease
- Single, round, discrete lesions without spiculation (Acta Cytol 2002;46:377)
- Usually no DCIS or elastosis (J Clin Pathol 2007;60:1333)