Breast malignant, males, children

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Breast malignant, males, children

Male tumors

Male papilloma

Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 18 November 2012, last major update August 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.

Definition
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● Usually presents with bloody nipple discharge

Terminology
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● Classified in WHO breast classification as central, peripheral or atypical papilloma (PubCan)

Case reports
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● 14 year old boy with enlarging breast mass (J Pediatr Surg 2011;46:e33)
● 57 year old man with intracystic papilloma associated with phenothiazine (Breast Cancer 2006;13:84)

Micro description
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● Identical to papillomas in women: multiple papillae in complex arborizing pattern with well-developed vascular connective tissue core surrounded by epithelial and myoepithelial cells; benign nuclei, frequentapocrine metaplasia, inflammationIdentical to papillomas in women

Micro images
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Various images

AFIP images:

Complex intraductal papilloma

Papillary tumor with fibrovascular core

Electron microscopy description
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● Epithelial cells, myoepithelial cells and intermediate cells with intranuclear helioid inclusions
● Squamous metaplasia (Ultrastruct Pathol 1994;18:601)

End of Breast malignant, males, children > Male tumors > Male papilloma

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