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Breast malignant, males, children

In situ carcinoma

Micropapillary DCIS

Reviewer: Dina Kandil, M.D. (see Reviewers page)
Revised: 8 November 2012, last major update January 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.


● 25% of cases involve multiple quadrants of breast (multicentric)

Micro description

● Tufts of proliferating epithelial cells projecting into the ductal lumen, without fibrovascular cores, characteristic of true papillary lesions
● These micropapillae are narrow at the base and have bulbous expansion at the tip resembling a club
● Tips of epithelial tufts may fuse together, forming “bridges” and “arcades”
● Cells are uniform and evenly distributed
● Usually low grade DCIS without necrosis
● Can be associated with flat epithelial atypia (Mod Pathol 2007;20:1149)

Micro images


Various images

No true fibrovascular cores

Roman bridges

Within a papilloma

Apocrine features

With cribriform DCIS

With hypersecretory features

With columnar cell change

Discontinuous fragments related to plane of sectioning

Micropapillae lack fibrovascular cores, cells are homogeneous

Cytology images

Nipple discharge shows high nuclear grade micropapillary DCIS (Giemsa stain)

End of Breast malignant, males, children > In situ carcinoma > Micropapillary DCIS

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