Breast malignant, males, children
In situ carcinoma
Micropapillary DCIS

Author: Dina Kandil, M.D. (see Authors page)

Revised: 27 September 2018, last major update January 2012

Copyright: (c) 2002-2018,, Inc.

PubMed Search: Micropapillary DCIS

Cite this page: Kandil, D. Micropapillary DCIS. website. Accessed October 23rd, 2018.
Gross description
  • 25% of cases involve multiple quadrants of breast (multicentric)
Microscopic (histologic) description
  • Tufts of proliferating epithelial cells projecting into the ductal lumen, without fibrovascular cores, characteristic of true papillary lesions
  • These micropapillae are narrow at the base and have bulbous expansion at the tip resembling a club
  • Tips of epithelial tufts may fuse together, forming ìbridgesî and ìarcadesî
  • Cells are uniform and evenly distributed
  • Usually low grade DCIS without necrosis
  • Can be associated with flat epithelial atypia (Mod Pathol 2007;20:1149)
Microscopic (histologic) images

Images hosted on PathOut server:

Courtesy of Mark R. Wick, M.D.

Discontinuous fragments related to plane of sectioning

Micropapillae lack
fibrovascular cores,
cells are homogeneous

Images hosted on other servers:

No true fibrovascular cores

Roman bridges

Cytology images

Images hosted on other servers:

Nipple discharge shows
high nuclear grade, Giemsa