Home > Breast malignant, males, children > Micropapillary DCIS
Breast malignant, males, children
In situ carcinoma
Micropapillary DCIS

Author: Dina Kandil, M.D. (see Authors page)

Revised: 18 October 2016, last major update January 2012

Copyright: (c) 2002-2016, PathologyOutlines.com, Inc.

PubMed Search: Micropapillary DCIS

Table of Contents
Gross description | Microscopic (histologic) description | Microscopic (histologic) images | Cytology images
Cite this page: Micropapillary DCIS. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantmicropapillaryDCIS.html. Accessed July 14th, 2017.
Gross description
  • 25% of cases involve multiple quadrants of breast (multicentric)
Microscopic (histologic) description
  • Tufts of proliferating epithelial cells projecting into the ductal lumen, without fibrovascular cores, characteristic of true papillary lesions
  • These micropapillae are narrow at the base and have bulbous expansion at the tip resembling a club
  • Tips of epithelial tufts may fuse together, forming ìbridgesî and ìarcadesî
  • Cells are uniform and evenly distributed
  • Usually low grade DCIS without necrosis
  • Can be associated with flat epithelial atypia (Mod Pathol 2007;20:1149)
Microscopic (histologic) images

Images hosted on PathOut server:

 

Courtesy of Mark R. Wick, M.D.

Discontinuous fragments related to plane of sectioning

Micropapillae lack
fibrovascular cores,
cells are homogeneous



Images hosted on other servers:

 

No true fibrovascular cores

Roman bridges

Cytology images

Images hosted on other servers:

Nipple discharge shows
high nuclear grade, Giemsa

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