Cite this page: Micropapillary DCIS. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantmicropapillaryDCIS.html. Accessed April 23rd, 2017.
- 25% of cases involve multiple quadrants of breast (multicentric)
- Tufts of proliferating epithelial cells projecting into the ductal lumen, without fibrovascular cores, characteristic of true papillary lesions
- These micropapillae are narrow at the base and have bulbous expansion at the tip resembling a club
- Tips of epithelial tufts may fuse together, forming ìbridgesî and ìarcadesî
- Cells are uniform and evenly distributed
- Usually low grade DCIS without necrosis
- Can be associated with flat epithelial atypia (Mod Pathol 2007;20:1149)