Breast malignant, males, children
In situ carcinoma
Mammary intraepithelial neoplasia (MIN)

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 18 October 2016, last major update January 2012

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PubMed Search: Mammary intraepithelial neoplasia

Table of Contents
Terminology
Cite this page: Mammary intraepithelial neoplasia (MIN). PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantmin.html. Accessed December 2nd, 2016.
Terminology
  • A general term to include both ductal and lobular intraepithelial neoplasia (Am J Surg Pathol 1991;15:209)
  • Mammary intraepithelial neoplasia, NOS refers to lesions with intermediate or overlapping ductal and lobular features (Hum Pathol 2002;33:620)
  • Some can be classified based on immunostains as ductal (E-cadherin+, high MW keratin-) or lobular (E-cadherin-, HMW keratin+), but others cannot
  • May have classic histological changes of DCIS and LCIS merging in single lobular duct systems (Am J Surg Pathol 1980;4:241)
  • Terminology is also used to describe type of mice (multiple intestinal neoplasia)