Breast malignant, males, children
Malignant Peripheral Nerve Sheath Tumor (MPNST)
Reviewer: Monika Roychowdhury, M.D. (see Reviewers page)
Revised: 7 November 2012, last major update November 2012
Copyright: (c) 2001-2012, PathologyOutlines.com, Inc.
● Very rare in breast
● Most cases are not associated with neurofibromatosis
● Not part of WHO breast classification
● 19 year old woman (J Med Assoc Thai 2006;89:377)
● 38 year old woman (World J Surg Oncol 2007;5:142)
● 56 year old woman with 30 cm tumor (Br J Radiol 2007;80:e44)
30 cm tumor
Alternating hyper and hypocellular areas with palisading spindle shaped cells and intervening myxoid areas; cells are S100+ (inset)
Hyperchromatic and pleomorphic wavy nuclei with mitoses
End of Breast malignant, males, children > Sarcoma > Malignant Peripheral Nerve Sheath Tumor (MPNST)
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