Table of Contents
Definition / general | Epidemiology | Clinical features | Microscopic (histologic) images | Differential diagnosisCite this page: Mucinous DCIS. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantmucinousDCIS.html. Accessed July 14th, 2017.
Definition / general
- DCIS with extracellular mucin production
- Mucin is usually in lumens of ducts involved by DCIS; also in vessels
- There are few studies of this entity (Histopathology 1996;29:533)
Epidemiology
- Mean age 62 years
- Predominant histologic types are solid, cribriform and micropapillary
- DCIS grading - low grade / 1 (29%), intermediate grade / 2 (61%), high grade / 3 (10%)
Clinical features
- Often associated with neovascularization in intraluminal mucin, although the presence of vascularized mucin in a needle biopsy cannot differentiate between in situ and invasive disease (Histopathology 2008;53:545)
Microscopic (histologic) images
Differential diagnosis
- Invasive mucinous carcinoma: mucin is in direct contact with stroma, and tumor cells are floating in mucin



