Breast malignant, males, children
Carcinoma subtypes
Neuroendocrine carcinoma - solid type

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 28 October 2016, last major update August 2012

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PubMed Search: Neuroendocrine carcinoma solid type

Cite this page: Neuroendocrine carcinoma - solid type. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantneuroendocrinesolid.html. Accessed December 8th, 2016.
Definition / General
  • Neuroendocrine carcinomas with 50%+ neuroendocrine differentiation (based on chromogranin or synaptophysin staining), and densely cellular solid nests or trabeculae separated by a delicate fibrovascular stroma
Terminology
  • This is a distinct WHO diagnostic category
Clinical Features
Case Reports
Micro Description
  • Densely cellular solid nests and trabeculae, or spindled, plasmacytoid or large cells, separated by a delicate fibrovascular stroma
  • Rarely rosettes or other features resembling carcinoid tumor
  • May originate from solid papillary DCIS or resemble alveolar subtype of lobular carcinoma
Micro Images

Images hosted on Nature servers:

Various stains (fig a, b, g, h, i)



Images hosted on other servers:

Various images

Cytology Description
  • Dyscohesive polygonal cells with abundant cytoplasm, many containing eosinophilic granules located at one pole (Malays J Pathol 2008;30:57)