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Breast malignant, males, children
Carcinoma subtypes
Oncocytic carcinoma

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 30 December 2016, last major update August 2012

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PubMed search: oncocytic [title] carcinoma breast

Table of Contents
Definition / general | Epidemiology | Prognostic factors | Case reports | Microscopic (histologic) description | Microscopic (histologic) images | Positive stains | Negative stains | Electron microscopy description | Differential diagnosis | Additional references
Cite this page: Oncocytic carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantoncocyticcarcinoma.html. Accessed July 14th, 2017.
Definition / general
  • Composed of 70%+ oncocytic cells
  • Also called malignant oncocytoma
Epidemiology
  • Very rare (< 20 cases reported), usually age 60+ years
Prognostic factors
  • Usually high grade (grade 3)
Case reports
Microscopic (histologic) description
  • Well circumscribed, abundant granular eosinophilic cytoplasm and low grade nuclei with conspicuous nucleoli (Am J Surg Pathol 1998;22:221)
  • Similar to apocrine carcinoma on H&E, but different staining pattern
  • No / rare mitotic figures
Microscopic (histologic) images

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Salivary gland oncocytic carcinoma

Positive stains
Negative stains
Electron microscopy description
  • Numerous mitochondria dispersed throughout cell, occupying 60%+ of cytoplasm
Differential diagnosis
Additional references
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