Breast malignant, males, children
Carcinoma subtypes
Oncocytic carcinoma

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 30 December 2016, last major update August 2012

Copyright: (c) 2001-2016, PathologyOutlines.com, Inc.

PubMed search: oncocytic [title] carcinoma breast

Cite this page: Oncocytic carcinoma. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantoncocyticcarcinoma.html. Accessed May 30th, 2017.
Definition / general
  • Composed of 70%+ oncocytic cells
  • Also called malignant oncocytoma
Epidemiology
  • Very rare (< 20 cases reported), usually age 60+ years
Prognostic factors
  • Usually high grade (grade 3)
Case reports
Microscopic (histologic) description
  • Well circumscribed, abundant granular eosinophilic cytoplasm and low grade nuclei with conspicuous nucleoli (Am J Surg Pathol 1998;22:221)
  • Similar to apocrine carcinoma on H&E, but different staining pattern
  • No / rare mitotic figures
Microscopic (histologic) images

Images hosted on other servers:

Salivary gland oncocytic carcinoma

Positive stains
Negative stains
Electron microscopy description
  • Numerous mitochondria dispersed throughout cell, occupying 60%+ of cytoplasm
Differential diagnosis
Additional references