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General
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Terminology
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Epidemiology
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Treatment and prognosis
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Case reports
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Clinical images
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Breast skin, courtesy of Dr. Mark R. Wick

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Eczematoid lesion

Gross description
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Micro description
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Micro images
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Breast skin, courtesy of Dr. Mark R. Wick

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Pseudobullous, courtesy of Dr. Mark R. Wick

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Invasive, courtesy of Dr. Mark R. Wick

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PAS, courtesy of Dr. Mark R. Wick

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CK7, courtesy of Dr. Mark R. Wick

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Large atypical cells in epidermis

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With hyperkeratosis and dermal inflammation

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With underlying comedo DCIS

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H&E and stains

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Derived from LCIS

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CK7+, E-cadherin negative

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CK7+



AFIP
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Involvement of entire thickness of epidermis, with pseudoepitheliomatous hyperplasia and hyperkeratosis with involved area, but not in normal appearing area

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Large atypical cells in epidermis have round nuclei and prominent nucleoli

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Involvement of terminal portion of lactiferous duct

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HER2+



Contributed by Dr. Semir Vranic - Paget's with underlying DCIS:
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H&E

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CK8+

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HER2+

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S100-

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Underlying DCIS (left to right): H&E, ER alpha, CK8, HER2

Videos
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Positive stains
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Negative stains
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EM description
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Differential diagnosis
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Additional references
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End of Breast malignant, males, children > In situ carcinoma > Paget's disease



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