Breast malignant, males, children
Breast cancer
Prognostic factors - Angiolymphatic invasion

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 20 October 2016, last major update February 2012

Copyright: (c) 2002-2016,, Inc.

PubMed Search: Angiolymphatic invasion

Cite this page: Prognostic factors - Angiolymphatic invasion. website. Accessed August 15th, 2018.
Definition / general
Microscopic (histologic) images

Images hosted on PathOut servers:

Not angiolymphatic invasion, but shrinkage
artifact with partly necrotic tumor in space created
by shrinkage; no endothelial cells are present, elastic
stain highlights elastic tissue in walls of vessels (AFIP)

Images hosted on Flickr:

Tumor in vessel wall (left), post-chemotherapy (right), courtesy of Dr. Semir Vranic

Images hosted on Nature servers:

Various images

Blood vessel versus
lymphatic vascular invasion

D2-40 stains endothelium of lymphatic but not artery or vein

D2-40+ lymphatics without tumor emboli at advancing front of tumor

D2-40+ lymphatics containing tumor emboli

Tumor emboli within tumor

Images hosted on other servers:

Various images

Cuff of lymphatic invasion around a small vein in a vascular bundle

CD31 and D2-40

Not angiolymphatic invasion

Retraction artifact