Breast malignant, males, children
Carcinoma subtypes
Tall cell like tumors

Author: Monika Roychowdhury, M.D. (see Authors page)

Revised: 30 December 2016, last major update August 2012

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PubMed Search: tall cell variant of papillary thyroid carcinoma
Cite this page: Tall cell like tumors. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastmalignantthyroidliketumors.html. Accessed January 18th, 2017.
Definition / General
Terminology
  • Not part of WHO breast classification
Clinical Features
Micro Description
  • Solid or papillary nests of columnar / cuboidal cells with eosinophilic granular cytoplasm, round / oval nuclei with sharply defined nuclear membrane, nuclear grooves and eosinophilic pseudoinclusions
  • Also psammoma bodies
Cytology Description
  • Abundant cellularity with isolated cells, sheets and papillary formations of epithelial cells with nuclear grooves (Int J Surg Pathol 2006;14:79)
Positive Stains
Negative Stains
Electron Microscopy Description
  • Cytoplasmic granules are mitochondria
Molecular / Cytogenetics Description
  • No BRAF mutations of thyroid carcinoma
Differential Diagnosis
  • Metastatic tall cell variant of papillary thyroid carcinoma: clinical history of thyroid disease, thyroglobulin+, TTF1+ (Ann Pathol 1998;18:130)