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Breast-nonmalignant
Inflammatory / infectious
Mondor’s disease
Reviewer: Hind Nassar, M.D. in January 2009 (see Authors page)
Revised: 28 September 2012, last major update April 2010
Copyright: (c) 2002-2010, PathologyOutlines.com, Inc.
Definition
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● Rare; thrombophlebitis of superficial veins of breast and adjacent thoracoabdominal wall
Terminology
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Epidemiology
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● 1% of oncologic breast cases and aesthetic mammoplasties (Aesthet Surg J 2009;29:209)
Sites
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Etiology
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Venous channels
Clinical features
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● Sudden onset of firm, painful, nodular cord beneath skin
● Self-limited, only rarely recurs
● May be related to trauma, such as radical mastectomy, but not associated with breast cancer
Prognostic factors
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Case reports
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● 55 year old woman with onset after core biopsy (AJR Am J Roentgenol 2002;179:185)
Treatment
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● Anti-inflammatory drugs, excision of thrombosed vein or no treatment (Eur J Gynaecol Oncol 2005;26:213)
Clinical images
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Cord on lateral breast Cords between breast and abdomen
Shallow linear depression 53 year old man
Gross description (Macroscopy)
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Gross images
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Micro description (Histopathology)
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● Phlebitis with thrombosis
● Late recanalization occurs
Micro images
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Drawings
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Virtual Slides
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Videos
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Cytology description
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Cytology images
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Positive stains
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Negative stains
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Electron microscopy descriptions
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Electron microscopy images
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Molecular / cytogenetics description
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Molecular / cytogenetics images
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Differential Diagnosis
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Additional references
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End of Breast-nonmalignant > Inflammatory / infectious > Mondor’s disease
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