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General
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Epidemiology
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Etiology
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Clinical features
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Case reports
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Treatment
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Gross description
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Micro description
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Micro images
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Courtesy of Dr. Mark R. Wick

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Circumscribed and polypoid lesion

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Proliferation of epithelial and myoepithelial cells

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With myoepithelial hyperplasia

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Duct hyperplasia w/ minimal sclerosis at recent biopsy site

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Epithelium without atypia in dilated (upper), duct below nipple

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Mixed pattern with papilloma (upper), sclerosis (center) and adenosis (right side)

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Compact arrays of ductules in adenosis lesion beneath intact nipple epidermis

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Focal necrosis in hyperplastic duct

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Papillomatosis with adenosis

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With atypical hyperplasia due to disorderly growth pattern without stroma

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With DCIS and Pagetís disease (arrow) in adult man

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p63 shows intact myoepithelial layer

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Patchy CK 5/6 staining of myoepithelium

Positive stains
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Negative stains
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Differential diagnosis
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Additional references
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End of Breast - nonmalignant > Benign tumors / changes > Nipple adenoma / florid papillomatosis of nipple



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