Breast - nonmalignant
Benign tumors / changes
Phyllodes tumor - borderline

Author: Hind Nassar, M.D. (see Authors page)

Revised: 10 August 2017, last major update April 2010

Copyright: (c) 2002-2017, PathologyOutlines.com, Inc.

PubMed Search: Phyllodes borderline [title] tumor breast

See also: Phyllodes - generalPhyllodes - benignPhyllodes - malignant

Nassar, H. Phyllodes tumor - borderline. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastphyllodesborderline.html. Accessed August 19th, 2017.
Definition / general
  • Has features intermediate between benign and malignant phyllodes tumors
Terminology
  • May be considered low grade malignant tumors
Clinical features
Treatment
  • Wide local excision
Microscopic (histologic) description
  • Moderate cellularity (between benign and malignant), 1 - 5 mitotic figures/10 HPF, partially or entirely infiltrative border
Microscopic (histologic) images

Images hosted on other servers:


Borderline tumor


H&E and p53 staining

Ki67 - Fig A: Benign tumor with minimal nuclear staining
Fig B: Low grade malignant tumor with increased Ki67
Fig C: High grade malignant tumor with frequent staining

Virtual slides

Images hosted on other servers:

Cystosarcoma phyllodes borderline

Molecular / cytogenetics description