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Definition
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Terminology
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Epidemiology
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Etiology
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Clinical features
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Prognostic factors
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Case reports
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Treatment
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Gross images
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Tumors with hemorrhage and necrosis

Malignant

Micro description
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Micro images
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Hypercellular tumor with stromal overgrowth, atypia and mitotic figures

Multinucleated giant cells

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Squamous metaplasia and keratin cysts

Osteochondroid metaplasia

Sarcomatous stroma


Pleomorphic nuclei

Infiltration into adipose tissue

Mitotic figures and abnormal mitotic figure

Multinucleated giant cells


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Chondrosarcoma component

Fibrosarcomatous stroma


Liposarcoma component

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MFH component

Osteosarcoma component


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Rhabdomyosarcoma component

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Sarcoma NOS component


Contributed by: Dr. Semir Vranic


Metastasis to thyroid Hurthle cell tumor

Ki-67, Fig A: benign tumor with minimal nuclear staining, Fig B: low grade malignant tumor with increased Ki-67, Fig C: high grade malignant tumor with frequent staining


p53+

p53

c-kit+ stromal cells and stromal giant cells






Cytology description
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Positive stains
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Molecular / cytogenetics description
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Differential diagnosis
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End of Breast - nonmalignant > Benign tumors / changes > Phyllodes Tumor - malignant



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