Breast nonmalignant
Inflammatory
Sarcoidosis


Topic Completed: 1 April 2010

Revised: 23 August 2019

Copyright: 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis [title] breast

Hind Warzecha, M.D.
Page views in 2018: 448
Page views in 2019 to date: 406
Cite this page: Warzecha H. Sarcoidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastsarcoidosis.html. Accessed August 25th, 2019.
Definition / general
  • Idiopathic systemic granulomatous disorder of noncaseating, epithelioid granulomas with multinucleated giant cells
  • Usually involves lungs with fibrosis; also lymph nodes, skin, liver, spleen, phalanges, bones, parotid gland
  • Rare in breast; either begins in breast or part of known disease
Clinical features
Radiology images

Contributed by Dr. Mark R. Wick

Mammogram

Case reports
Clinical images

Contributed by Dr. Mark R. Wick

Breast skin

Microscopic (histologic) description
  • Noncaseating, epithelioid granulomas with multinucleated giant cells
  • No / rare necrosis
Microscopic (histologic) images

Contributed by Dr. Mark R. Wick

Parenchyma

Breast skin



AFIP images

Stromal granulomas sparing lobules

DCIS (arrow) with sarcoid-like granuloma

Infiltrating lobular
carcinoma and
sarcoid-like
granuloma



Images hosted on other servers:

Nonnecrotizing granulomatous inflammation

Lymph node

Cytology description
  • Epithelioid cells and lymphocytes
Differential diagnosis
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