Breast - nonmalignant
Inflammatory / infectious
Sarcoidosis


Topic Completed: 1 April 2010

Revised: 14 January 2019

Copyright: (c) 2002-2019, PathologyOutlines.com, Inc.

PubMed Search: Sarcoidosis [title] breast
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Cite this page: Nassar H Sarcoidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastsarcoidosis.html. Accessed April 24th, 2019.
Definition / general
  • Idiopathic systemic granulomatous disorder of noncaseating, epithelioid granulomas with multinucleated giant cells
  • Usually involves lungs with fibrosis; also lymph nodes, skin, liver, spleen, phalanges, bones, parotid gland
  • Rare in breast; either begins in breast or part of known disease
Clinical features
Radiology images

Contributed by Dr. Mark R. Wick

Mammogram

Case reports
Clinical images

Contributed by Dr. Mark R. Wick

Breast skin

Microscopic (histologic) description
  • Noncaseating, epithelioid granulomas with multinucleated giant cells
  • No / rare necrosis
Microscopic (histologic) images

Contributed by Dr. Mark R. Wick

Parenchyma

Breast skin


Stromal granulomas sparing lobules

DCIS (arrow) with sarcoid-like granuloma

Infiltrating lobular
carcinoma and
sarcoid-like
granuloma



Images hosted on other servers:

Nonnecrotizing granulomatous inflammation

Lymph node

Cytology description
  • Epithelioid cells and lymphocytes
Differential diagnosis
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