Sarcoidosis

Breast - nonmalignant
Inflammatory / infectious
Sarcoidosis

Author: Hind Nassar, M.D. (see Authors page)

Revised: 27 July 2017, last major update April 2010

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PubMed Search: Sarcoidosis [title] breast

Table of Contents

Cite this page: Sarcoidosis. PathologyOutlines.com website. http://www.pathologyoutlines.com/topic/breastsarcoidosis.html. Accessed August 17th, 2017.

Definition / general

Idiopathic systemic granulomatous disorder of noncaseating, epithelioid granulomas with multinucleated giant cells
Usually involves lungs with fibrosis; also lymph nodes, skin, liver, spleen, phalanges, bones, parotid gland
Rare in breast; either begins in breast or part of known disease

Clinical features

Abnormal breast examinations or mammograms present in 2% of sarcoidosis patients, granulomas in 1% (Sarcoidosis Vasc Diffuse Lung Dis 2001;18:301)
Occasionally begins in breast and remains localized for long periods
May mimic metastatic breast cancer (Clin Breast Cancer 2007;7:804)

Radiology images

Images hosted on PathOut server:

Mammogram, courtesy of Dr. Mark R. Wick

Case reports

41 year old woman with unusual presentation of sarcoidosis of the breast (Br J Radiol 2008;81:e231)
51 year old woman with sarcoidosis of the breast (Eur Rev Med Pharmacol Sci 2006;10:47)

Clinical images

Images hosted on PathOut server: