Reviewer: Nat Pernick, M.D. (see Reviewers page)
Revised: 30 August 2013, last major update February 2002
Copyright: (c) 2002-2013, PathologyOutlines.com, Inc.
PubMed Search: CD101[title]
- Also called immunoglobulin superfamily member 2 (IGSF2), V7
- Inhibits T cell activation induced by CD3, by (a) inhibiting IL-2RA expression on activated T cells and IL2 secretion (J Immunol 1998;161:209), (b) inducing IL10 production (Eur J Immunol 2000;30:3132)
- No significant clinical use by pathologists
CD4+ CD56+ blastic tumor cells
Positive staining (normal)
- Monocytes, granulocytes, dendritic cells, activated T lymphocytes in small intestine
Positive staining (disease)
End of CD Markers > CD101
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